TRIzol Products - US (2024)

TRIzol Products - US (1)

Invitrogen TRIzol products are referenced in thousands of journal publications, reflecting the trust that molecular biologists have placed in TRIzol Reagent to deliver high-quality, intact RNA from many kinds of biological materials.

TRIzol reagents are offered in several ready-to-use formats. The individual products within the TRIzol reagent family are tailored to isolate total RNA or to simultaneously isolate RNA, DNA, and protein from diverse biological sources, including samples of human, animal, plant, yeast, bacterial, and viral origin.

TRIzol infographics

RNA extraction product selection guide

  • TRIzolReagent
  • TRIzol LSReagent
  • TRIzol PhasemakerTubes
  • TRIzol Plus RNAPurification System
  • TRIzol Max BacterialRNA Isolation Kit
ProductTRIzol Products - US (2)
TRIzol Reagent
DescriptionIsolates total RNA from tissues or cells, including lipid-rich and difficult samples
Primary Sample Type
  • Bacteria
  • Blood
  • Cells
  • Plant Samples
  • Tissue
  • Viral Samples
  • Yeast
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size100 mL or 200 mL
Purification Time1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
Order Now
ProductTRIzol Products - US (3)
TRIzol LS Reagent
DescriptionDesigned for use with liquid samples, such as serum or virus preparations
Primary Sample Type
  • Blood
  • Liquid Samples (e.g. Serum)
  • Viral Samples
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size100 mL or 200 mL
Purification Time1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
Order Now
ProductTRIzol Products - US (4)
TRIzol Phasemaker Tubes
DescriptionCreates a tight, durable seal between the aqueous and organic phase of your TRIzol mix, allowing the RNA to be easily removed and maintaining TRIzol reagent's performance
Primary Sample TypeAll sample types processed using any TRIzol reagent
Product SizePre-dispensed, 2 mL tubes
Order Now

Meet a great match for TRIzol reagents: Phasemaker Tubes

Using TRIzol reagents just got simpler, thanks to a new best friend. Invitrogen Phasemaker Tubes create a tight, durable seal between the aqueous and organic phase of your TRIzol mix. Phasemaker Tubes don’t compromise the performance of TRIzol reagents, allowing you to easily pipette off the RNA phase. It’s almost too easy.

Save money by purchasing Phasemaker Tubes together with TRIzol, TRIzol LS, or TRIzol Plus reagents, or use them with your existing TRIzol reagent.

TRIzol Products - US (5)

The benefits of using Phasemaker Tubes include:

  • Higher yield—increase recovery by as much as 30%
  • Ease of use—simply use with TRIzol mix, centrifuge, and then easily pipette off the aqueous phase
  • Ready-to-use convenience—comes predispensed in 2 mL tubes
  • Increased throughput—stable gel seal allows you to maximize the number of samples per run without losing phase separation
ProductTRIzol Products - US (6)
TRIzol Plus RNA Purification System
DescriptionOffers rapid isolation of total RNA by combining the lysis capability of TRIzol Reagent with the convenient RNA extraction technology of the Invitrogen PureLink RNA Mini Kit silica spin column
Primary Sample Type
  • Bacteria
  • Cells
  • Plant Samples
  • Tissue
  • Yeast
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size100 mL or 200 mL
Purification Time1 hour
Application
  • Microarray Analysis
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
Order Now
ProductTRIzol Max Bacterial RNA Isolation Kit
DescriptionOffers rapid isolation of total RNA by combining the lysis capability of TRIzol Reagent with the convenient RNA extraction technology of the Invitrogen PureLink RNA Mini Kit silica spin column
Primary Sample TypeBacteria
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size100 preps or 200 preps
Purification Time1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
Order Now

TRIzolReagent

ProductTRIzol Products - US (7)
TRIzol Reagent
DescriptionIsolates total RNA from tissues or cells, including lipid-rich and difficult samples
Primary Sample Type
  • Bacteria
  • Blood
  • Cells
  • Plant Samples
  • Tissue
  • Viral Samples
  • Yeast
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size100 mL or 200 mL
Purification Time1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
Order Now

TRIzol LSReagent

ProductTRIzol Products - US (8)
TRIzol LS Reagent
DescriptionDesigned for use with liquid samples, such as serum or virus preparations
Primary Sample Type
  • Blood
  • Liquid Samples (e.g. Serum)
  • Viral Samples
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size100 mL or 200 mL
Purification Time1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
Order Now

TRIzol PhasemakerTubes

ProductTRIzol Products - US (9)
TRIzol Phasemaker Tubes
DescriptionCreates a tight, durable seal between the aqueous and organic phase of your TRIzol mix, allowing the RNA to be easily removed and maintaining TRIzol reagent's performance
Primary Sample TypeAll sample types processed using any TRIzol reagent
Product SizePre-dispensed, 2 mL tubes
Order Now

Meet a great match for TRIzol reagents: Phasemaker Tubes

Using TRIzol reagents just got simpler, thanks to a new best friend. Invitrogen Phasemaker Tubes create a tight, durable seal between the aqueous and organic phase of your TRIzol mix. Phasemaker Tubes don’t compromise the performance of TRIzol reagents, allowing you to easily pipette off the RNA phase. It’s almost too easy.

Save money by purchasing Phasemaker Tubes together with TRIzol, TRIzol LS, or TRIzol Plus reagents, or use them with your existing TRIzol reagent.

TRIzol Products - US (10)

The benefits of using Phasemaker Tubes include:

  • Higher yield—increase recovery by as much as 30%
  • Ease of use—simply use with TRIzol mix, centrifuge, and then easily pipette off the aqueous phase
  • Ready-to-use convenience—comes predispensed in 2 mL tubes
  • Increased throughput—stable gel seal allows you to maximize the number of samples per run without losing phase separation

TRIzol Plus RNAPurification System

ProductTRIzol Products - US (11)
TRIzol Plus RNA Purification System
DescriptionOffers rapid isolation of total RNA by combining the lysis capability of TRIzol Reagent with the convenient RNA extraction technology of the Invitrogen PureLink RNA Mini Kit silica spin column
Primary Sample Type
  • Bacteria
  • Cells
  • Plant Samples
  • Tissue
  • Yeast
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size100 mL or 200 mL
Purification Time1 hour
Application
  • Microarray Analysis
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
Order Now

TRIzol Max BacterialRNA Isolation Kit

ProductTRIzol Max Bacterial RNA Isolation Kit
DescriptionOffers rapid isolation of total RNA by combining the lysis capability of TRIzol Reagent with the convenient RNA extraction technology of the Invitrogen PureLink RNA Mini Kit silica spin column
Primary Sample TypeBacteria
Final Product
  • Total RNA
  • Transcriptome RNA
  • Micro RNA
Product Size100 preps or 200 preps
Purification Time1 hour
Application
  • Cloning
  • Northern Blotting
  • Nuclease Protection Assays
  • Real-Time Quantitative PCR (qPCR)
  • Reverse Transcriptase PCR (RT-PCR)
  • cDNA Library Construction
Order Now

Featured videos

TRIzol Products - US (12)

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Phasemaker Tubes create a durable seal between the aqueous and organic phases, allowing researchers to easily pipette off the RNA phase.

TRIzol Products - US (2024)

FAQs

What is the alternative to TRIzol? ›

G2PzolTM is a cost-effective, single-step RNA isolation reagent that serves as a suitable alternative to TrizolTM , a commonly used RNA isolation reagent.

Who is the manufacturer of TRIzol? ›

TRIZOL is supplied by the company, Aura Biotech. RNA extraction from TRISOL has long been considered the gold standard for RNA purification.

What is the other name of TRIzol? ›

TRIzol® - the Gold (Pink) Standard

So much so that other commercial companies offer similar reagents with their own nomenclature (TRI Reagent®, RNAzol®, QIAzol®, TriPure, TriSure, etc.). The all-in-one reagent offers excellent capability to lyse a variety of complex samples.

Is TRIzol and QIAzol the same? ›

The most widely known of these products is TRIzol® (also called TRI Reagent®, RNAzol®, QIAzol® and sold by many different companies). TRIzol® is an all-in-one acid-guanidinium-phenol solution that combines the hom*ogenization solution and phenol addition of the original no-kit protocol into one step.

Why is TRIzol toxic? ›

Guandinium thiocyanate, one of the two components of TRIzol®, is corrosive to the skin and eyes and is toxic by inhalation, ingestion, and dermal exposure.

What is the difference between TRIzol and TRIzol LS? ›

The only difference between TRIzol Reagent and TRIzol LS Reagent is the concentration of the components. TRIzol LS Reagent is slightly more concentrated and designed to isolate total RNA, DNA, and proteins from liquid samples. TRIzol LS Reagent is slightly darker than TRIzol Reagent.

What is the shelf life of TRIzol? ›

Studies indicate that TRIzol LS is stable at room temperature for up to 12 months. However, at 4°C TRIzol LS reagent is stable for 2 years.

Is tri reagent the same as TRIzol? ›

What does TRI Reagent® do? TRI Reagent® solution (also sold as TRIzol) is a mixture of a mixture of guanidine thiocyanate and phenol in a monophase solution that is used for the isolation of DNA, RNA and protein from biological samples of human, animal, plant, yeast, bacteria, and virus. It inhibits RNase activity.

How long is RNA stable in TRIzol? ›

Sample hom*ogenization step: If samples are efficiently lysed in TRIzol® Reagent and the reagent inactivates the nucleases, you can safely store RNA for 3–4 days at room temperature. RNA precipitation step: You can store RNA in isopropanol overnight at 4°C.

Why add chloroform to TRIzol? ›

During tissue hom*ogenization or lysis, the TRIzol reagent maintains RNA integrity, while disrupting cells and dissolving cell components. Addition of chloroform followed by centrifugation separates the solution into an aqueous phase and an organic phase.

What does TRIzol smell like? ›

TRIzol is light-sensitive and is often stored in a dark-colored, glass container covered in foil. It is stored at room temperature. When used, it resembles cough syrup, bright pink. The smell of the phenol is extremely strong.

What is inside TRIzol? ›

TRIzol (or TRI Reagent) is a monophasic solution of phenol and guanidinium isothiocyanate that simultaneously solubilizes biological material and denatures protein.

What happens if you get TRIzol on your skin? ›

Trizol is a highly corrosive and toxic chemical that can cause burns on contact with the skin as well as systemic poisoning. Details of the incident are below. Reportedly the incident took place after hours while the researcher was working alone.

Does TRIzol degrade protein? ›

During sample hom*ogenization or lyses, Trizol maintains the integrity of the RNA, DNA, and proteins, while disrupting cells and dissolving cell components.

Which is better QIAzol or RLT buffer? ›

If lysis is not a problem then RLT is the best option. otherwise, QIAzol is normally preferred in case you have lysis problem. like in case of fatty tissues. As far as I know Qiazol is optimized to retrieve also small RNAs while the RLT is used for isolation of >200nt RNAs (in our lab at least).

What is an alternative to trichloroethane? ›

EnTron™ Non-Flammable Critical Cleaning Solvent has almost exactly the same favorable physical characteristics, cleaning performance, and compatibility with metals, plastics and elastomers as 1,1,1 trichloroethane, without any of the negative effects on the environment associated 1,1,1 trichloroethane.

What is the alternative to triazolam? ›

Are there alternative medicines to triazolam? There are other medicines that may be used for sleep problems such as zopiclone or temazepam (which is a benzodiazepine). These are best used occasionally and for a short time.

Is Tri reagent the same as TRIzol? ›

What does TRI Reagent® do? TRI Reagent® solution (also sold as TRIzol) is a mixture of a mixture of guanidine thiocyanate and phenol in a monophase solution that is used for the isolation of DNA, RNA and protein from biological samples of human, animal, plant, yeast, bacteria, and virus. It inhibits RNase activity.

Why TRIzol is not used in DNA extraction? ›

TRIzol is infrequently used to extract DNA from tissue because of the low purity of the extracted DNA and the time-consuming procedure.

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